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所長挨拶

最大限のホスピタリティでお迎えします

2010年4月1日、東静岡駅南口前に聖隷健康サポートセンターShizuokaを開設させていただき、多くのみなさまのご支援のもと、お陰さまで開設8年目を迎えることができましたことを心より感謝申し上げます。聖隷保健事業部の静岡県中部における拠点の一つとして、中部地区の予防医療の充実を図るべく、職員一同、努力してまいりますので、どうぞ宜しくお願い申し上げます。

当施設は総合保健施設として、人間ドック・健康診断・検診車による巡回健診の実施、保健師・管理栄養士・健康運動指導士等による生活習慣改善のお手伝いはもとより、健診後の再検査やフォローアップのご要望にもお応えできる体制、禁煙外来などを順次整えております。また、女性専用検査をまとめたレディスフロアを設け、オリジナルの健診着を使用するなど、女性が安心してご利用していただける施設を目指しております。

さらに、当施設の特徴でもありますクリニック部門を併設し、各種専門外来(呼吸器外来、禁煙外来、除菌外来、婦人科外来)での診療も行っております。

また、昨年より新しい人間ドックメニューとして「宿泊ドック」、新しいオプション検査として「アルコール分解酵素遺伝子検査」を始めました。今後も利用者様のニーズに合わせ、様々なオプション検査が選択できるよう努めてまいります。

東静岡駅南口前という大変アクセスのよい場所で、最新の高度医療機器を設置し、臨床経験豊富な各科専門医・検査技師による精度の高い医療技術・診断のご提供、そして、皆様により快適にご利用いただけますよう最大限のホスピタリティを持ちまして、皆様のご利用をお待ち申し上げます。


プロフィール

聖隷健康サポートセンターShizuoka 所長 鈴木美香

学歴1996年3月浜松医科大学医学部医学科卒業
2003年3月浜松医科大学大学院医学系研究科修了
経歴1996年5月浜松医科大学医学部付属病院 産婦人科
1996年6月静岡県立総合病院 麻酔蘇生科
1996年10月鹿児島市立病院 産婦人科・新生児科
1997年4月掛川市立総合病院 産婦人科
1997年10月鹿児島市立病院 産婦人科
1998年8月国立豊橋病院 産婦人科
2003年4月米国カリフォルニア大学サンディエゴ校医学部
がんセンター(UCSD Cancer Center)
2006年4月聖隷健康診断センター
2008年10月聖隷健康サポートセンターShizuoka 開設準備室室長
2010年4月聖隷健康サポートセンターShizuoka 所長
その他の役職等2015年3月特定非営利活動法人 くすり・たべもの・からだの協議会理事

主な資格等
医学博士。労働衛生コンサルタント。日本産科婦人科学会専門医。日本東洋医学会漢方専門医。日本臨床細胞学会細胞診専門医。日本女性医学学会女性ヘルスケア専門医。検診マンモグラフィ読影認定医(評価AS)。社会医学系指導医・専門医。日本医師会認定産業医。日本医師会認定健康スポーツ医。人間ドック健診指導医。人間ドック健診情報管理指導士。浜松医科大学・大学院非常勤講師。静岡大学学校医。静岡県立大学客員教授。
主な受賞歴
日本癌治療学会優秀演題賞、国際線溶溶解学会Poster Award (ドイツ)
国際健診学会奨励賞 (中国)

業績

原著論文
1Montel V, Suzuki M, Galloy C, Mose ES, Tarin D. Expression of melanocyte-related gene in human breast cancer and its implications. Differentiation. 78(5):283-91, 2009.
2Suzuki M, Mose E, Galloy C, Tarin D. Osteopontin gene expression determines spontaneous metasttic performance of orthotopic human breast cancer xenografts. Am J Pathol. 171(2):682-692, 2007.
3Suzuki M, Tarin D. Gene expression profiling of human lymph node metastases and matched primary breast carcinomas: Clinical implications. Mol Oncol. 1:172-180, 2007.
4Suzuki M, Montel V, Tarin D. Dormant cancer cells retrieved from metastasis-free organs regain tumorigenic and metastatic potency. Am J Pathol. 169(2):673-81, 2006.
5Kobayashi H, Yoshida R, Kanada Y, Fukuda Y, Yagyu T, Inagaki K, Kondo T, Kurita N, Suzuki M, Kanayama N, Terao T. Suppression of lipopolysaccharide-induced cytokine production of gingival fibroblasts by a soybean, Kunitz trypsin inhibitor. J Periodontal Res. 40(6):461-8, 2005.
6Kobayashi H, Yoshida R, Kanada Y, Fukuda Y, Yague T, Inagaki K, Kondo T, Kurita N, Yamada Y, Sado T, Kitanaka T, Suzuki M, Kanayama N, Terao T. A soy bean Kunits trypsin inhibitor reduces tumor necrosis factor- production in ultoraviolet-exposed primary human keratinocytes. Exp Dermatol. 14(10):765-74, 2005.
7Omatsu K, Kobayashi T, Murakami Y, Suzuki M, Ohashi R, Sugimura M, Kanayama N. Phosphatidylserine/phosphatidylcholine microvesicles can induce preeclampsia-like changes in pregnant mice. Semin Thromb Hemost. 31(3):314-20, 2005.
8Murakami Y, Kobayashi T, Omatsu K, Suzuki M, Ohashi R, Matsuura T, Sugimura M, Kanayama N. Exogenous vascular endothelial growth factor can induce preeclampsia-like symptoms in pregnant mice. Semin Thromb Hemost. 31(3):307-13, 2005.
9Matsuzaki H, Kobayashi H, Yagyu T, Wakahara K, Kondo T, Kurita N, Sekino H, Inagaki K, Suzuki M, Kanayama N, Terao T. Reduced syndecan-1 expression stimulates heparin-binding growth factor-mediated invasion in ovarian cancer cells in a urokinase-independent mechanism. Oncol Rep. 14(2):449-57, 2005.
10Inagaki K, Kobayashi H, Yoshida R, Kanada Y, Fukuda Y, Yagyu T, Kondo T, Kurita N, Kitanaka K, Yamada Y, Sakamoto Y, Suzuki M, Kanayama N, Terao T. Suppression of urokinase expression and invasion by a soybean kunitz trypsin inhibitor is mediated through inhibition of Src-dependent signaling pathways. J Biol Chem. 280(36):31428-37, 2005.
11Kobayashi H, Yoshida R, Kanada Y, Fukuda Y, Yagyu T, Inagaki K, Kondo T, Kurita N, Suzuki M, Kanayama N, Terao T. Suppressing effects of daily oral supplementation of beta-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis in mouse model. J Cancer Res Clin Oncol. 131(8):527-38, 2005.
12Kobayashi H, Yoshida R, Kanada Y, Fukuda Y, Yagyu T, Inagaki K, Kondo T, Kurita N, Suzuki M, Kanayama N, Terao T. Dietary supplementation of soybean kunitz trypsin inhibitor reduces lipopolysaccharide-induced lethality in mouse model. Shock. 23(5):441-447, 2005.
13Matsuzaki H, Kobayashi H, Yagyu T, Wakahara K, Kondo T, Kurita N, Sekino H, Inagaki K, Suzuki M, Kanayama N, Terao T. Plasma bikunin as a favorable prognostic factor in ovarian cancer. J Clin Oncol. 23(7):1463-72, 2005.
14Wakahara K, Kobayashi H, Yagyu T, Matsuzaki H, Kondo T, Kurita N, Sekino H, Inagaki K, Suzuki M, Kanayama N, Terao T. Bikunin suppresses lipopolysaccharide-induced lethality through down-regulation of tumor necrosis factor- alpha and interleukin-1 beta in macrophages. J Infect Dis. 191(6):930-8, 2005.
15Yagyu T, Kobayashi H, Matsuzaki H, Wakahara K, Kondo T, Kurita N, Sekino H, Inagaki K, Suzuki M, Kanayama N, Terao T. Thalidomide inhibits tumor necrosis factor-alpha-induced interleukin-8 expression in endometriotic stromal cells, possibly through suppression of nuclear factor-kappaB activation. J Clin Endocrinol Metab. 90(5):3017-21, 2005.
16Wakahara K, Kobayashi H, Yagyu T, Matsuzaki H, Kondo T, Kurita N, Sekino H, Inagaki K, Suzuki M, Kanayama N, Terao T. Bikunin down-regulates heterodimerization between CD44 and growth factor receptors and subsequently suppresses agonist-mediated signaling. J Cell Biochem. 94(5):995-1009, 2005.
17Matsuzaki H, Kobayashi H, Yagyu T, Wakahara K, Kondo T, Kurita N, Sekino H, Inagaki K, Suzuki M, Kanayama N, Terao T. Bikunin inhibits lipopolysaccharide-induced tumor necrosis factor alpha induction in macrophages. Clin Diagn Lab Immunol. 11(6):1140-7, 2004.
18Suzuki M, Kobayashi H, Tanaka Y, Kanayama N, Terao T. Reproductive failure in mice lacking inter-alpha-trypsin inhibitor (ITI)--ITI target genes in mouse ovary identified by microarray analysis. J Endocrinol. 183(1):29-38, 2004.
19Yagyu T, Kobayashi H, Wakahara K, Matsuzaki H, Kondo T, Kurita N, Sekino H, Inagaki K, Suzuki M, Kanayama N, Terao T. A kunitz-type protease inhibitor bikunin disrupts ligand-induced oligomerization of receptors for transforming growth factor (TGF)-beta and subsequently suppresses TGF-beta signalings. FEBS Lett. 576(3):408-16, 2004.
20Kobayashi H, Fukuda Y, Yoshida R, Kanada Y, Nishiyama S, Suzuki M, Kanayama N, Terao T. Suppressing effects of dietary supplementation of soybean trypsin inhibitor on spontaneous, experimental and peritoneal disseminated metastasis in mouse model. Int J Cancer. 112(3):519-24, 2004.
21Wakahara K, Kobayashi H, Yagyu T, Matsuzaki H, Kondo T, Kurita N, Sekino H, Inagaki K, Suzuki M, Kanayama N, Terao T. Transforming growth factor-beta1-dependent activation of Smad2/3 and up-regulation of PAI-1 expression is negatively regulated by Src in SKOV-3 human ovarian cancer cells. J Cell Biochem. 93(3):437-53, 2004.
22Tanaka Y, Kobayashi H, Suzuki M, Kanayama N, Suzuki M, Terao T. Upregulation of bikunin in tumor-infiltrating macrophages as a factor of favorable prognosis in ovarian cancer. Gynecol Oncol. 94(3):725-34, 2004.
23Kobayashi H, Suzuki M, Terao T. A soybean Kunitz trypsin inhibitor suppresses ovarian cancer cell invasion by blocking urokinase upregulation. Clin. Exp. Metastasis 21(2):159-66, 2004.
24Kobayashi H, Yagyu T, Inagaki K, Kondo T, Suzuki M, Kanayama N, Terao T. Bikunin plus paclitaxel markedly reduce tumor burden and ascites in mouse model of ovarian cancer. Int. J. Cancer 110(1): 134-139, 2004.
25Tanaka Y, Kobayashi H, Suzuki M, Hirashima Y, Kanayama N, Terao T. Genetic downregulation of pregnancy-associated plasma protein-A (PAPP-A) by bikunin reduces IGF-I-dependent Akt and ERK1/2 activation and subsequently reduces ovarian cancer cell growth, invasion and metastasis. Int. J. Cancer 109(3): 336-47, 2004.
26Kobayashi H, Yagyu T, Inagaki K, Kondo T, Suzuki M, Kanayama N, Terao T. Therapeutic efficacy of once-daily oral administration of a Kunitz-type protease inhibitor, bikunin, in a mouse model and in human cancer. Cancer 100(4): 869-877, 2004.
27Suzuki M, Kobayashi H, Kanayama N, Saga Y, Suzuki M, Lin CY, Dickson RB, Terao T. Inhibition of tumor invasion by genomic downregulation of matriptase through suppression of activation of receptor-bound pro-urokinase. J. Biol. Chem. 279(15): 14899-14908, 2004.
28Tanaka Y, Kobayashi H, Suzuki M, Kanayama N, Terao T. Transforming growth factor-beta 1-dependent urokinase up-regulation and promotion of invasion are involved in Src-MAPK-dependent signaling in human ovarian cancer cells. J. Biol. Chem. 279(10): 8567-8576, 2004.
29Kobayashi H, Suzuki M, Kanayama N, Terao T. Genetic down-regulation of phoshoinositide-3-kinase by Bikunin correlates with suppression of invasion and metastasis in human ovarian cancer HRA cells. J. Biol. Chem. 279(8): 6371-6379, 2004.
30Tanaka Y, Kobayashi H, Suzuki M, Kanayama N, Suzuki M, Yamakawa T, Morishita H, Terao T. Reduced bikunin gene expression as a factor of poor prognosis in ovarian carcinoma. Cancer 98(2): 424-430, 2003.
31Hirashima Y, Kobayashi H, Suzuki M, Tanaka Y, Kanayama N, Terao T. Transforming growth factor-beta1 (TGF-beta 1) produced by ovarian cancer cell line HRA stimulates attachment and invasion through an upregulation of plasminogen activator inhibitor type-1 (PAI-1) in human peritoneal mesothelial cells. J. Biol. Chem. 278(29): 26793-802, 2003.
32Kobayashi H, Suzuki M, Hirashima Y, Terao T. The protease inhibitor bikunin, a novel anti-metastasis agent. Biol. Chem. 384(5): 749-754, 2003.
33Suzuki M, Kobayashi H, Tanaka Y, Hirashima Y, Kanayama N, Takei Y, Saga Y, Suzuki M, Itoh H, Terao T. Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cell line by overexpression of bikunin. Int. J. Cancer 104(3) 289-302, 2003.
34Sun GW, Kobayashi H, Suzuki M, Kanayama N, Terao T. Follicle-stimulation hormone and insulin-like growth factor I synergistically induce up-regulation of cartilage link protein (Crtl1) via activation of phoshatidylinositol-dependent kinase/Akt in rat granulose cells. Endocrinology 144(3): 793-801, 2003.
35Suzuki M, Kobayashi H, Tanaka Y, Hirashima Y, Kanayama N, Takei Y, Saga Y, Suzuki M, Itoh H, Terao T. Bikunin target genes in ovarian cancer cells identified by microarray analysis. J. Biol. Chem. 278(17): 14640-46, 2003.
36Kobayashi H, Suzuki M, Tanaka Y, Kanayama N, Terao T. A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking calcium-dependent transforming growth factor (TGF)-beta 1 signaling cascade. J Biol. Chem. 278(10):7790-9, 2002.
37Kobayashi H, Suzuki M, Kanayama N, Nishida T, Takigawa M, Terao T. CD44 stimulation by fragmented hyaluronic acid induces upregulation of urokinase-type plasminogen activator and its receptor and subsequently facilitates invasion of human chondrosarcoma cells. Int. J. Cancer 102(4): 379-89, 2002.
38Sun GW, Kobayashi H, Suzuki M, Kanayama N, Terao T. Production of cartilage link protein by human granulose-lutein cells. J Endocrinol. 175(2): 505-15, 2002.
39Tanaka Y, Kobayashi H, Suzuki M, Kanayama N, Suzuki M, Terao T. Thymidine phosphorylase expression in tumor-infiltrating macrophage may be correlated with poor prognosis in uterine endometrial cancer. Human Pathology 33(1): 1105-13, 2002.
40Sun GW, Kobayashi H, Suzuki M, Kanayama N, Terao T. Link protein as an enhancer of cumulus cell-oocyte complex expansion. Mol. Reprod. Dev. 63(2):223-31, 2002.
41Suzuki M, Kobayashi H, Kanayama N, Nishida T, Takigawa M, Terao T. CD44 stimulation by fragment hyaluronic acid induces upregulation and tyrosine phosphorylation of c-Met receptor protein in human chondrosarcoma cells. Biochim. Biophys. Acta. 159(1-3):37-44, 2002.
42Kobayashi H, Suzuki M, Kanayama N, Nishida T, Takigawa M, Terao T. Suppression of urokinase receptor expression by bikunin is associated with inhibition of upstream targets of extracellular signal-regulated kinase-dependent cascade. Eur. J. Biochim. 269(16); 3945-57, 2002.
43Suzuki M, Kobayashi H, Fujie M, Nishida T, Takigawa M, Kanayama N, Terao T. Kunitz-type protease inhibitor bikunin disrupts phorbor ester-induced oligomerization of CD44 variant isoforms containing epitope v9 and subsequently suppresses expression of urokinase-type plasminogen activator in human chondrosarcoma cells. J. Biol. Chem. 277(10): 8022-32, 2002.
44Suzuki M, Kobayashi H, Kageyama S, Shibata K, Fujie M, Terao T. Excretion of bikunin and its fragments in the urine of patients with renal stones. J. Urol. 166(1): 268-74, 2001.
45Suzuki M, Kobayashi H, Tanaka Y, Hirashima Y, Terao T. Structure and function analysis of urinary trypin inhibitor (UTI): identification of binding domains and signaling property of UTI by analysis of truncated proteins. Biochem. Biophys. Acta. 1547(1): 26-36, 2001.
46Hirashima Y, Kobayashi H, Suzuki M, Tanaka Y, Kanayama N, Fujie M, Nishida T, Takigawa M, Terao T. Characterization of binding properties of urinary trypsin inhibitor to cell-associated binding sites on human chondrosarcoma cell line HCS-2/8. J. Biol. Chem. 276(17): 13650-6, 2001.
47Kobayashi H, Suzuki M, Tanaka Y, Hirashima Y, Terao T. Suppression of urokinase expression and invasiveness by urinary trypsin inhibitor is mediated through inhibition of protein kinase C-and MEK/ERK/c-Jun-dependent signaling pathways. J. Biol. Chem. 276(3): 2015-22, 2001.
48Kobayashi H, Suzuki M, Sun GW, Hirashima Y, Terao T. Suppression of urokinase-type plasminogen activator expression from human ovarian cancer cells by urinary trypsin inhibitor. Biochim. Biophys. Acta. 1481(2): 310-6, 2000.

受賞歴

2001年日本癌治療学会にて優秀演題賞受賞
2002年金原一郎記念医学医療振興財団より第16回研究交流助成金受理
内藤記念科学振興財団より若手研究者海外派遣助成金受理
病態代謝研究会より海外留学補助金受理
Poster Award from 16th International Congress of the
InternationalSociety for Fibrinolysis and Proteolysis(ドイツ)
2003年神澤医学研究振興財団より第6回研究助成金受理
国際ロータリー財団より国際親善奨学金受理
2004年上原記念生命科学財団より海外留学助成金受理
2005年かなえ医療振興財団より海外留学助成金受理
2008年第23回国際健診学会にて奨励賞受賞(北京にて)

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